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KMID : 0829220150390030551
Korean Journal of Oral and Maxillofacial Pathology
2015 Volume.39 No. 3 p.551 ~ p.558
Histopathologic Comparison of Osteomyelitis, Osteoradionecrosis, Medication-Related Osteonecrosis of the Jaw
À¯Å¹Î:You Tae-Min
±èÇö½Ç:Kim Hyun-Sil
Abstract
Osteonecrosis is defined as non-vital bone tissue as a result of abnormal process of osseous healing, and is caused by several reasons such as infection, radiation, and medication. Osteomyelitis, osteoradionecrosis, and medication related osteonecrosis of the jaws (MRONJ) which have necrotic bone in common are confused clinically due to similar symptoms and radiographic findings, and are difficult to diagnose definitively. Because each disease represents a separate clinical progress and requires a different treatment approach, it is very important to distinguish each disease. The aim of this study was to analyze the histopathologic features of osteomyelitis, osteoradionecrosis, MRONJ and to understand their different pathogenesis.
KEYWORD
Osteonecrosis, Osteomyelitis, Osteoradionecrosis, Medication Related Osteonecrosis of the Jaws, Pathophysiology
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